Can pleural effusions be reliably detected using point-of-care ultrasound (POCUS)?

Absolutely. Though costophrenic blunting may not be seen on a PA or AP chest radiography until more than 200 mL of pleural effusion is present, as little as 20 mL of pleural fluid can be reliability detected with POCUS, with a sensitivity of 100% when more than 100 mL is present. Most pleural effusions will accumulate in the dependent areas within the chest cavity. Thus, in the usual semi-recumbent position used for POCUS, pleural effusion will accumulate above the diaphragm and below the lower lobe of the lungs.1,2

Few things to consider when evaluating for pleural effusion. 

  • Because evaluation for pleural effusions may require imaging depths of 10 to 20 cm, low frequency (preferably a phased array) transducer should be used.
  • Place the transducer in the posterior axillary line around the level of the diaphragm with the orientation marker positioned cephalad in the coronal plane (FIGURE 1).
  • Identify the diaphragm and use it as a point of reference to minimize mistakes such as labeling ascites as pleural effusion. Structures above the diaphragm (atelectatic lung, pleural effusion) will be shown on the left while structures below the diaphragm (abdominal organs, ascites) will be shown on the right side of the ultrasound display (FIGURE 2).
  • Keep in mind that freely flowing atelectatic lung tip (jellyfish sign) and spine shadows (spine sign) may be visible (VIDEO 1). Anechoic, free flowing pleural effusions are categorized as simple while homogeneously and heterogeneously echogenic effusions or those with septations are categorized as complex (VIDEO 2 and VIDEO 3). 2,3 
  • Smaller effusions may be seen as a small anechoic layer of fluid between the chest wall and the lung. If you use the M-mode, you will find that the lung moves towards or away from the chest wall in a wave like pattern (sinusoid sign) (VIDEO 4).1

Bonus Pearl: Did you know that you can estimate pleural effusion volume by using the following formula: Volume=16 x distance from mid lung base to the diaphragm (mm)? 4

Contributed by Woo Moon, D.O, Director, Hospitalist and Internal Medicine Residency Point-of-Care Ultrasound Programs, Mercy Hospital-St. Louis, St. Louis, Missouri

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     Figure 1                                                         Figure 2

Figure 3

Video 1

 

Video 2

 

Video 3

 

Video 4

 

References

  1. Soni NJ, Arntfield R, Kory P. Point of Care Ultrasound. 2nd ed. St. Louis, MO: Elsevier; 2019.
  2. Soni NJ, Franco R, Velez MI, et al. Ultrasound in the diagnosis and management of pleural effusions. J Hosp Med 2015;10(12):811–6. Ultrasound in the diagnosis and management of pleural effusions – PubMed (nih.gov) 
  3. Yang PC, Luh KT, Chang DB, Wu HD, et al. Value of sonography in determining the nature of pleural effusion: analysis of 320 cases. AJR Am J Roentgenol 1992;159(1):29–33.     Value of sonography in determining the nature of pleural effusion: analysis of 320 cases – PubMed (nih.gov)
  4. Usta E, Mustafi M, Ziemer G. Ultrasound estimation of volume of postoperative pleural effusion in cardiac surgery patients. Interact Cardiovasc Thorac Surg 2010;10(2):204–7. Ultrasound estimation of volume of postoperative pleural effusion in cardiac surgery patients – PubMed (nih.gov).

Disclosures/Disclaimers: The listed questions and answers are solely the responsibility of the author and do not necessarily represent the official views of Mercy Hospital-St. Louis, Massachusetts General Hospital, Harvard Catalyst, Harvard University, their affiliate academic healthcare centers, or its contributors. Although every effort has been made to provide accurate information, the author is far from being perfect. The reader is urged to verify the content of the material with other sources as deemed appropriate and exercise clinical judgment in the interpretation and application of the information provided herein. No responsibility for an adverse outcome or guarantees for a favorable clinical result is assumed by the author. Thank you!

Can pleural effusions be reliably detected using point-of-care ultrasound (POCUS)?

How do I assess the left ventricular (LV) systolic function by bedside point-of-care ultrasound (POCUS)?

You can assess the LV systolic function by POCUS by just zeroing in on the following cardiac parameters: 1. Anterior mitral valve leaflet motion in early diastole; 2. Change in LV chamber diameter; and 3. LV wall thickness during systole.1

First assess the anterior mitral valve leaflet motion towards the interventricular septum in early diastole in the parasternal long axis view (Figure). Estimated or measured distance between anterior mitral valve leaflet and the interventricular septum is called E-point septal separation (EPSS). When LV systolic function is normal, anterior mitral valve leaflet opens fully in early diastole, resulting in a small or minimal separation between it and the interventricular septum. Due to the fixed length of the chordae and the enlarged LV chamber size, anterior mitral valve leaflets are unable to fully open as systolic function worsens. This results in increased separation between the anterior mitral valve leaflet and the interventricular septum. An estimated EPSS greater than 10 mm is considered abnormal and suggests LV dysfunction.1,2

You can also estimate the LV ejection fraction (LVEF) quantitatively  by utilizing the following formula:3

LVEF (%)=75.5 – 2.5xEPSS (mm)

Keep in mind that aortic insufficiency and mitral stenosis can affect the accuracy of this formula.1

As for assessing the LV chamber diameter and wall thickness, recall that these parameters are also dynamic throughout the cardiac cycle. In systole, LV diameter should decrease by 30-40% while LV wall thickness should increase by approximately 40%. Using this as a guide, you can perform qualitative assessment by “eyeballing” the LV systolic function in parasternal long axis, parasternal short axis, apical 4-chamber and subcostal 4-chamber views. Beware that in parasternal long axis, apical 4-chamber and subcostal 4-chamber views, off axis of images can foreshorten the chamber size, resulting in overestimation of systolic function. Also be sure to use the midventricular papillary muscle view when assessing systolic function in the parasternal short axis.1   

Once you have obtained all the necessary images, feel free to categorize the systolic function as either “hyperdynamic”, “normal”, “reduced” or “severely reduced” (watch video below).1

Bonus pearl:  Did you know that qualitative assessment of the LV systolic function  following brief training sessions have been shown to significantly correlate with that obtained by formal echocardiography (k = 0.77, p <0.001).1,4,5 

Contributed by Woo Moon, D.O, Director POCUS Training Program, Mercy-St. Louis Hospital, St. Louis, Missouri

Figure: EPSS in normal vs reduced EF 

Note: EPSS (yellow arrows) is narrow in normal but wide in reduced EF

Video: Four categories of systolic function

 

References

  1. Soni MD MS NJ, Arntfield MD FRCPC R, Kory MD MPA P. Point of Care Ultrasound. 2nd ed. St. Louis, MO: Elsevier; 2019. . https://www.elsevier.com/books/point-of-care-ultrasound/soni/978-0-323-54470-2
  2. Kimura BJ, Yogo N, O’Connell CW, Phan JN, Showalter BK, Wolfson T. Cardiopulmonary limited ultrasound examination for “quick-look” bedside application. Am J Cardiol 2011;108(4):586–90. https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(11)01424-X
  3. Silverstein JR, Laffely NH, Rifkin RD. Quantitative estimation of left ventricular ejection fraction from mitral valve E-point to septal separation and comparison to magnetic resonance imaging. Am J Cardiol 2006;97(1):137–40. https://www.ajconline.org/article/S0002-9149(05)01683-8/fulltext
  4. Melamed R, Sprenkle MD, Ulstad VK, Herzog CA, Leatherman JW. Assessment of left ventricular function by intensivists using hand-held echocardiography. Chest 2009;135(6):1416–20. https://journal.chestnet.org/article/S0012-3692(09)60341-X/fulltext 
  5. Johnson BK, Tierney DM, Rosborough TK, Harris KM, Newell MC. Internal medicine point-of-care ultrasound assessment of left ventricular function correlates with formal echocardiography. J Clin Ultrasound 2016;44(2):92–9. https://onlinelibrary.wiley.com/doi/10.1002/jcu.22272

 

 

 

 

 

 

 

How do I assess the left ventricular (LV) systolic function by bedside point-of-care ultrasound (POCUS)?